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Abstract #1142

Influence of Breast Cancer Receptor Status on Multi-parametric Magnetic Resonance Imaging for Predicting Treatment Response: Preliminary Results

Xia Li 1 , Vandana G Abramson 1 , Lori R. Arlinghaus 1 , Hakmook Kang 1 , Jason M Williams 1 , Richard G Abramson 1 , A. Bapsi Chakravarthy 1 , Praveen Pendyala 1 , and Thomas E Yankeelov 1

1 Vanderbilt University, Nashville, Tennessee, United States

This study determines if classifying breast cancer patients by subtype improves the ability of integrated DCE-MRI and DW-MRI to predict eventual response after the first cycle of NAC. The patients were divided into three groups according to receptor status: 1) ER-/PR-/HER2-, 2) HER2+, and 3) HR+/HER2-. These preliminary results demonstrate that DCE- and DW-MRI may be able to better predict treatment response for patients with particular receptor status. This observation should be confirmed in a large cohort in the future.

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