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Abstract #1149

A Novel Prostate MR Elastography Technique Based on Image Similarity

Seyed Reza Mousavi 1 , Seyyed Mohammad Hesabgar 2 , Timothy Scholl 2,3 , and Abbas Samani 2,3

1 Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada, 2 Medical Biophysics, University of Western Ontario, London, Ontario, Canada, 3 Robarts Research Institute, London, Ontario, Canada

T2-weighted MR imaging is an evolving modality in prostate cancer diagnosis. Although T2-weighted MRI has a good sensitivity but it has low specificity. The specificity of the T2-weighted MRI, however, may be improved by calculating prostate tissue elasticity distribution. Tissue elasticity properties are known to be prostate cancer biomarkers. In this research project, an MR elastography technique is proposed to reconstruct tissue Youngs modulus with the aim of improving T2-weighted MR imaging specificity. The proposed technique only utilizes T2-weighted MR imaging information and does not require any additional peripheral devices. It also does not appreciably disrupt the clinical flow.

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