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Abstract #1157

Diagnostic performance of 68Ga-PSMA-PET/MRI versus 68Ga-PSMA-PET/CT in the evaluation of lymph node and bone metastases of prostate cancer

Martin Thomas Freitag 1 , Jan Radtke 1,2 , Boris Hadaschik 2 , Uwe Haberkorn 3 , Heinz-Peter Schlemmer 1 , Matthias Roethke 1 , and Ali Afshar-Oromieh 3

1 Department of Radiology, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany, 2 Department of Urology, University hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany, 3 Department of Nuclear Medicine, University hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

The recently introduced 68Gallium-PSMA-ligand is regarded as a significant step forward in the diagnosis of prostate cancer and its metastases for PET examinations. Multiparametric PET/MR could be advantageous over PET/CT to better delineate PET-positive findings due to higher soft tissue contrast. Here, we systematically compare the diagnostic performance of multiparametric PET/MRI versus PET/CT with focus on bone and lymph node metastases of prostate cancer. PET-positive results were significantly correlating between both methods indicating a strong reliability of PET-measurements using 68Ga-PSMA-PET/MRI. For the delineation of lymph nodes, PET/MRI was superior to PET/CT whereas the conspicuity of bone metastases was comparable.

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