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Abstract #1185

Ultra structure of articular cartilage

Soorena Azam Zanganeh 1 , Chantal Pauli 2 , Christine B Chung 3 , Eric Chang 3 , Graeme M Bydder 3 , Darryl DLima 2 , and Jiang Du 3

1 Radiology, University of California, San Diego, San Diego, CA, United States, 2 Department of Molecular and Experimental Medicine, the Scripps Research Institute, San Diego, CA, United States, 3 Radiology, University of California, San Diego, San Diego, CA, United Kingdom

Articular cartilage with its special structure has been studied for different layers including superficial zone which fibers are parallel to surface,transitional zone with random fibers or curved fibers and deep zone fibers are perpendicular to the surface . structures which are good explanation of magic angle effect when fibers are oriented at 54 degree. As an importance of vertical striation with different magic angel effect we investigate the fiber structure of articular cartilage using polarized light microscopy and high resolution magnetic resonance imaging plus histology.for histology we used the Safranine O-Green staining with PLM of medial and lateral tibial plateau which are the surfaces are covered whit menisci.

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