Abstract #1186
Multi-Echo SWI of Knee Cartilage
Joanna Yuen 1 , Jachin Hung 2 , Vanessa Wiggermann 1,2 , Robert McCormack 3 , Agnes d'Entremont 4,5 , and Alexander Rauscher 1,2
1
UBC MRI Research Centre, Vancouver, British
Columbia, Canada,
2
Department
of Physics and Astronomy, The University of British
Columbia, Vancouver, British Columbia, Canada,
3
Department
of Orthopaedics, The University of British Columbia,
Vancouver, British Columbia, Canada,
4
Department
of Mechanical Engineering, The University of British
Columbia, Vancouver, British Columbia, Canada,
5
Centre
for Hip Health and Mobility, Vancouver, British
Columbia, Canada
The frequency of susceptibility-weighted MR signal has
proven to be highly sensitive to changes in tissue
microstructure, which may reflect pathologic changes. We
explored the potential of a multi-echo SWI to image
articular cartilage damage. Four patients were scanned
on a 3T scanner. MR signal magnitude, frequency, and T2*
maps were generated and compared to arthroscopic video.
Grade I, II, and III changes were detected in
arthroscopy, average magnitude, and T2* maps, while
Grade II and III changes were observable on MR frequency
maps. This study demonstrates the use of different SW
contrasts to visualize OA-related changes in knee
cartilage.
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