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Abstract #1217

A comparison of three approaches for defining nucleus pulposus and annulus fibrosus on sagittal MR images.

Yi-Xiang Wang 1 , Greta SP Mok 2 , Duo Zhang 2 , Shu-Zhong Chen 1 , and Jing Yuan 3

1 Dept Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, 2 Department of Electrical and Computer Engineering, University of Macau, Macau SAR, Macau, 3 Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong

We compared three region-of-interest (ROI) methods for nucleus pulposus (NP) and annulus fibrosus (AF). Fifty-two subjects were imaged under a 3-T MRI and a total of 256 discs were evaluated using manual and uniform ROI methods to define NP and AF. The intra-class correlation coefficient (ICC) values were all >0.75 when comparing 5-/7-ROI with manual ROI methods for NP, and 0.167-0.488 for AF when comparing 7-ROI with M-ROI method. The values increased to 0.378-0.582 for 5-ROI method. Comparable results were obtained with Bland-Altman plots. The uniform ROI methods agreed well with manual ROI for NP but not for AF.

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