Abstract #1218
Assessment of the stiffness of intervertebral disk in rat model with Magnetic Resonance Elastography
Yifei Liu 1 , Julia Zelenakova 2 , Kejia Cai 2,3 , Robert Kleps 4 , Thomas J Royston 1,2 , Richard L Magin 2 , Andrew Larson 5 , and Weiguo Li 4,5
1
Department of Mechanical & Industrial
Engineering, University of Illinois at Chicago, Chicago,
Illinois, United States,
2
Department
of Bioengineering, University of Illinois at Chicago,
Chicago, Illinois, United States,
3
Department
of Radiology, University of Illinois at Chicago,
Chicago, IL, United States,
4
Research
Resource Center, University of Illinois at Chicago,
Chicago, Illinois, United States,
5
Department
of Radiology, Northwestern University, Chicago,
Illinois, United States
Biomechanical properties of the intervertebral disk
(IVD) can be a potential biomarker to access IVD
degeneration, one of most significant causes of lower
back pain. This study shows the feasibility and
promising results of using magnetic resonance
elastography (MRE), a non-invasive tissue stiffness
estimation technique, to measure the IVD stiffness in a
lumbar segment of a rat model.
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