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Abstract #1257

Influence of Respirations on Cerebrospinal Fluid (CSF) Movement Using bSSFP Time-Spatial Labeling Inversion Pulse (Time-SLIP)

Shinya Yamada 1 , Yuichi Yamashita 2 , Masao Yui 2 , Cheng Ouyang 3 , Masao Nakahashi 2 , and Mitsue Miyazaki 3

1 Toshiba Rinkan Hospital, Sagamihara, Kanagawa, Japan, 2 Toshiba Medical Systems Corp., Tochigi, Japan, 3 Toshiba Medical Research Institute, Illinois, United States

The effect of respiration on CSF movement was investigated using a non-contrast time-spatial labeling inversion pulse (Time-SLIP) with balanced steady-state free precession (bSSFP) cine readout. CSF moved cephalic (16.4 7.7 mm) during deep inhalation and caudal (11.6 3.0 mm) during deep exhalation in the prepontine cisternal area. Small but rapid cephalic (3.0 0.4 mm) and caudal (3.0 0.5 mm) movement was observed in the same region during breath holding. Time-SLIP bSSFP cine presents for non-invasive visualization of CSF movement associated during deep expiration and expiration to a degree not previously reported.

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