Evaluating Artifact Introduced by Intra-Subject Motion Correction in Functional MRI

In addition to magnetic susceptibility, a potential source of motion artifact could be image-processing operations. As one of most typical image process, spatial resampling is demanded by head-motion correction of functional images. It deals with interpolation among neighboring voxels, and could be problematic when local signal is not homogeneous. The goal of this study was to evaluate the spatial resampling process during motion correction, and to verify that this artifact occurs at areas can be easily affected by the partial volume effect. In order to exclude the effect of motor-related neural activity, simulation experiments were designed and three types of data were created corresponding to common types of head motion.

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