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Abstract #1260

Reliability and reproducibility of arterial transit time-corrected whole-brain pseudo-continuous arterial spin labeling

Kazunobu Tsuji 1 , Tatsuro Tsuchida 1 , Yasuhiro Fujiwara 1,2 , Masayuki Kanamoto 1 , Tsuyoshi Matsuda 3 , R. Marc Lebel 4 , and Hirohiko Kimura 1

1 Radiology, University of Fukui, Yoshida-gun, Fukui, Japan, 2 Medical Imaging, Kumamoto University, Kumamoto, Japan, 3 Global MR Applications and Workflow, GE Healthcare, Tokyo, Japan, 4 Global MR Applications and Workflow, GE Healthcare, AB, Canada

Arterial spin labeling (ASL) signals reflect blood flow delivery to local brain tissue, but may be affected by arterial transit time (ATT). Low-resolution ATT pre-scan has been proposed as a means of reducing the ATT contribution1. Reproducibility studies have recently been reported from several groups using different ASL schemes, but no reports have described the reproducibility of ATT and ATT-corrected CBF. This study was to assess the reproducibility and reliability of ATT and ATT-corrected CBF maps compared with those of uncorrected CBF calculated using fixed transit time delay.

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