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Abstract #1320

Characterization of white matter change and the adjacent white matter with diffusion tensor MRI

Shuzhong Chen 1 , Vincent Mok 2 , Yi-Xiang Wang 1 , Ka Sing Wong 2 , and Winnie CW Chu 1

1 Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, 2 Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong

The apparent diffusion coefficient (ADC) is elevated and fractional anisotropy (FA) is reduced in age-related white matter changes (WMC) regions has been reported. This study is to determine the FA, relative anisotropy (RA), volume ration (VR) and ADC in the regions of WMC and the adjacent white matter tissue. A voxel expanded label map was created to detect the change of adjacent white matter tissue of the WMC regions. The FA, RA, VR and ADC shows progressively change as the region expands.

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