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Abstract #1327

The effect of age on wide-view retinotopic mapping of central and periphery visual areas

Wei Zhou 1,2 , Eric R Muir 1,3 , Jinqi Li 1 , Crystal Franklin 1 , and Timothy Q Duong 1,2

1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States, 2 Radiology, University of Texas Health Science Center, San Antonio, Texas, United States, 3 Ophthalmology, University of Texas Health Science Center, San Antonio, Texas, United States

The purpose of this study was to investigate the effects of age on retinotopic mapping measurements with a relatively wide view to include central and periphery vision areas. By setting up wide-view checkboard stimulation, the boundaries of visual fields were defined. Our results demonstrated that central visual areas of older subjects exhibited weaker BOLD responses for central stimulation (0~45) but stronger BOLD responses for periphery stimulation (45~90), compared to younger subjects. These findings indicated there are central vision loss and neural reorganization with age.

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