Abstract #1360
Amygdala Functional Connectivity after Real-time fMRI Neurofeedback Emotional Training in Combat-Related PTSD
Raquel Phillips 1 , Vadim Zotev 1 , Kymberly Young 1 , Chung Ki Wong 1 , Brent Wurfel 1 , Matthew Meyer 1,2 , Frank Krueger 1,3 , Matthew Feldner 1,4 , and Jerzy Bodurka 1,5
1
Laureate Institute for Brain Research,
Tulsa, OK, United States,
2
Laureate
Psychiatric Clinic and Hospital, Tulsa, OK, United
States,
3
Dept.
of Psychology, George Mason University, Fairfax, VA,
United States,
4
Dept.
of Psychological Science, University of Arkansas,
Fayetteville, AR, United States,
5
College
of Engineering, University of Oklahoma, Tulsa, OK,
United States
We performed emotion regulation training in veterans
with combat-related PTSD using real-time fMRI
neurofeedback (rtfMRI-nf). Seven subjects in the
experimental group learned to upregulate left amygdala
activity using rtfMRI-nf based on retrieval of happy
autobiographical memories, while seven subjects in the
control group performed the rtfMRI-nf task with feedback
from the left horizontal segment of the intraparietal
sulcus. Functional connectivity analysis showed that for
the experimental group activity in the left amygdala was
more correlated with other regions of the brain during
positive memory recall following three sessions of
neurofeedback than it was in the control group.
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