Abstract #1382
The Value of Resting State-fMRI for Detecting Epileptogenic Zone in Patients with Focal Epilepsy
Jianzhong Yin 1,2 , Bofeng Zhao 1 , Zhijuan Chen 3 , Weidong Yang 3 , Yu Qing 4 , Li Cai 5 , Panli Zuo 6 , Hongyan Ni 1,2 , and Wen Shen 1,2
1
Radiology Department, Tianjin First Central
Hospital, Tianjin, Tianjin, China,
2
Tianjin
Medical Imaging Institution, Tianjin, China,
3
Department
of Neurosurgery, Tianjin Medical University General
Hospital, Tianjin, China,
4
Department
of Neurology, Tianjin Medical University General
Hospital, Tianjin, China,
5
Clinical
PET-CT Center, Tianjin Medical University General
Hospital, Tianjin, China,
6
MR
Collaboration, Siemens Healthcare China, Beijing, China
We made systematic comparison of the findings of resting
state fMRI with other localization techniques, including
VEEG, PET, and MRI, for epileptogenic zone. It revealed
that RS-MRI based on those analysis methods has almost
the same sensitivity of PET, and almost the same
specificity of VEEG for localization of epileptogenic
zone. Although there are still some way off for routine
usage, our findings suggest that RS-fMRI, which has the
advantages of non-invasiveness, fairly high spatial
resolution and easy implementation, could be a powerful
and efficient tool for further clinical application.
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