Mapping the g-ratio within MS lesions
Mara Cercignani 1 , Giovanni Giulietti 2 , Barbara Spano' 2 , and Marco Bozzali 2
CISC, Brighton and Sussex Medical School,
Brighton, East Sussex, United Kingdom,
Laboratory, Santa Lucia Foundation, Rome, Italy
The g-ratio is a reliable index of axonal myelination,
and can be related to the physiology and function of an
axon. Here we combine diffusion and magnetization
transfer to map the MS lesion g-ratio and relate it to
variable pathological substrates.
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