Abstract #1402

Mapping the g-ratio within MS lesions

Mara Cercignani ¹ , Giovanni Giulietti ² , Barbara Spano' ² , and Marco Bozzali ²

¹ CISC, Brighton and Sussex Medical School, Brighton, East Sussex, United Kingdom, ² Neuroimaging Laboratory, Santa Lucia Foundation, Rome, Italy

The g-ratio is a reliable index of axonal myelination, and can be related to the physiology and function of an axon. Here we combine diffusion and magnetization transfer to map the MS lesion g-ratio and relate it to variable pathological substrates.

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