Abstract #1420
Connectome-scale Assessment of Structural and Functional Connectivity in Mild Traumatic Brain Injury at the Acute Stage
Armin Iraji 1 , Hanbo Chen 2 , Natalie Wiseman 1 , Tuo Zhang 2 , Robert Welch 1 , Brian O'Neil 1 , Andrew Kulek 1 , Syed Imran Ayaz 1 , Xiao Wang 1 , Conor Zuk 1 , E. Mark Haacke 1 , Tianming Liu 2 , and Zhifeng Kou 1
1
Wayne State University, Detroit, Michigan,
United States,
2
University
of Georgia, Georgia, United States
Mild traumatic brain injury is a public healthcare
burden that costs the nation billions of dollars each
year. Numerous data using diffusion tensor imaging have
reported widely spread damage in major white matter
tracts, in suggestion of large-scale network disruptions
or alternations. However, very limited data investigated
the scale and extent of brain network changes after
mTBI. We used a novel approach to identifying the
large-scale brain network alternations in both structure
and function in mTBI patients at the acute stage. This
work represents the first effort to investigate the
scale and extent of brain network changes after mTBI.
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