Abstract #1421
Default-mode network functional connectivity progression in the days following a single sports concussion
Victoria L Morgan 1 , Andrew J Gregory 2 , and Allen K Sills 3
1
Institute of Imaging Science, Vanderbilt
University, Nashville, TN, United States,
2
Ortho-Sports
Medicine, Vnderbilt University, Nashville, TN, United
States,
3
Neurosurgery, Vanderbilt University,
Nashville, TN, United States
The purpose of this work is to quantify the functional
brain network changes in college student-athletes within
one week of a single sports concussion compared to
healthy college students. The results show that within
days of injury there were focal increases in functional
connectivity (FC) in parts of the default-mode network
(DMN) including the bilateral hippocampus, precuneus and
ventromedial prefrontal cortex. The average FC across
the whole DMN linearly increased over the first week,
but eventually returned to the range of the healthy
subjects in three subjects. Together these results
suggest a progression of DMN FC impairment and recovery.
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