Abstract #1454
Pulmonary MRI of Infants in the Neonatal Intensive Care Unit: Initial Experience with 3D Radial UTE
Andrew D. Hahn 1 , Nara S. Higano 2,3 , Laura L. Walkup 2 , Xuefeng Cao 2,4 , Robert P. Thomen 2,3 , Jean A. Tkach 5 , Charles L. Dumoulin 6,7 , Kevin M. Johnson 1 , Scott K. Nagle 1,8 , Jason C. Woods 2,3 , and Sean B. Fain 1,8
1
Department of Medical Physics, University of
Wisconsin - Madison, Madison, Wisconsin, United States,
2
Center
for Pulmonary Imaging Research, Cincinnati Childrens
Hospital Medical Center, Cincinnati, Ohio, United
States,
3
Department
of Physics, Washington University in St Louis, St.
Louis, Missouri, United States,
4
Department
of Physics, University of Cincinnati, Cincinnati, Ohio,
United States,
5
Department
of Radiology, Cincinnati Childrens Hospital Medical
Center, Cincinnati, Ohio, United States,
6
Imaging
Research Center - Department of Radiology, Cincinnati
Childrens Hospital Medical Center, Cincinnati, Ohio,
United States,
7
Department
of Pediatrics, University of Cincinnati, Cincinnati,
Ohio, United States,
8
Department
of Radiology, University of Wisconsin - Madison,
Madison, Wisconsin, United States
High isotropic resolution (<1mm) MRI of lung parenchymal
structure is performed in non-sedated neonatal intensive
care unit (NICU) patients using a unique, 1.5T neonatal
MRI system located within the CCHMC NICU and a 3-D
ultra-short echo time (UTE) pulse sequence.
Reconstructed images are retrospective respiratory gated
to end-expiration using self-navigation properties of
the center-out radial sequence. We demonstrate the
ability to generate diagnostic quality images at
resolution similar to computed tomography with the
presented approach, and show significant improvements
over previous methodology.
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