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Abstract #1460

Self-Gating of Respiratory Motion for Pulmonary Ultra Short Echo Time MRI of Infants in the NICU

Andrew D. Hahn 1 , Xuefeng Cao 2,3 , Nara S. Higano 2,4 , Jean A. Tkach 5 , Robert P. Thomen 2,4 , Scott K. Nagle 1,6 , Gregory Lee 2 , Kevin M. Johnson 1 , Sean B. Fain 1,6 , and Jason C. Woods 2,4

1 Department of Medical Physics, University of Wisconsin - Madison, Madison, Wisconsin, United States, 2 Center for Pulmonary Imaging Research, Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio, United States, 3 Department of Physics, University of Cincinnati, Cincinnati, Ohio, United States, 4 Department of Physics, Washington University in St Louis, St. Louis, Missouri, United States, 5 Department of Radiology, Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio, United States, 6 Department of Radiology, University of Wisconsin - Madison, Madison, Wisconsin, United States

The repeated sampling of the k-space center, or dc component, in 3-D center-out radial ultra short echo time (UTE) magnetic resonance imaging (MRI) can serve as a self-navigator for retrospective respiratory gating. We utilize this important feature to retrospectively reconstruct 3-D UTE pulmonary MRI at end-expiration and end-inspiration in non-sedated neonatal intensive care unit (NICU) patients, where respiratory rates, mechanical ventilation, and positioning can preclude bellows belt and pencil navigators. Gated images at end-inspiration and end-expiration provide estimates of tidal volumes and can better resolve structural abnormalities in bronchopulmonary dysplasia than ungated images.

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