Abstract #1462
Lung imaging at ultra-high magnetic fields in rodents
Marta Tibiletti 1 , Detlef Stiller 2 , Volker Rasche 1 , and Andrea Bianchi 2
1
Core Facility Small Animal MRI, Ulm
University, Ulm, Baden-Wrttemberg, Germany,
2
Target
Discovery Research, In-vivo imaging laboratory,
Boehringer Ingelheim Pharma GmbH & Co. KG,
Baden-Wrttemberg, Germany
In this work, we demonstrate the feasibility of
pre-clinical lung imaging at ultra-high magnetic fields
(11.7 T) using 3D ultra-short echo time (UTE) and zero
echo-time (ZTE) imaging. The results obtained at 11.7 T
resulted similar with the one acquired at 7 T in
comparable conditions. T2* relaxation time of lung at
these magnetic fields were also calculated with a
sequence of 3D UTE. ZTE images demonstrated lower SNR
than UTE images, but also to be more robust to motion
artifacts.
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