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Abstract #1473

Volumetric Non-Contrast Pulmonary Perfusion using pseudo-Continuous Arterial Spin Labeling

Joshua S. Greer 1,2 , Xinzeng Wang 2 , Ivan Pedrosa 2,3 , and Ananth J. Madhuranthakam 2,3

1 Bioengineering, UT Dallas, Dallas, TX, United States, 2 Radiology, UT Southwestern, Dallas, TX, United States, 3 Advanced Imaging Research Center, UT Southwestern, Dallas, TX, United States

Pulsed arterial spin labeling (PASL) techniques, such as 2D FAIRER, have been developed and evaluated in normal volunteers to study pulmonary perfusion at 1.5 T. However, PASL approaches are fundamentally limited to 2D acquisitions due to their reliance on the blood flow from outside the imaging volume, and cannot be extended to volumetric acquisitions. In this work, we present a non-contrast volumetric pulmonary perfusion using pseudo-continuous ASL labeling of the inferior vena cava in combination with a segmented 3D turbo spin echo acquisition at 3 T.

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