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Abstract #1540

High-Resolution Computed DWI with High b-Value: A Preliminary Study for Improving Prostate Cancer Detection at 3T MR System

Yoshiko Ueno 1 , Satoru Takahashi 2 , Yoshiharu Ohno 2,3 , Katsusuke Kyotani 4 , Masao Yui 5 , Yoshimori kassai 5 , Kazuhiro Kitajima 6 , and Kazuro Sugimura 1

1 Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, 2 Department of Radiology, Kobe University Graduate School of Medicine, Hyogo, Japan, 3 Advanced Biomedical Imaging Research, Kobe University Graduate School of Medicine, Hyogo, Japan, 4 Division of Radiology, Kobe University Hospital, Hyogo, Japan, 5 MRI Systems Development Department, Toshiba Medical Systems Corp, Tochigi, Japan, 6 Department of Radiology, Hyogo College of Medicine, Hyogo, Japan

Computed diffusion weighted imaging (cDWI) is proposed as a new technique that produces any b-value images from acquired DWI (aDWI) with at least two different b-values. Recently, high-resolution DWI of the prostate had potential for improving the sensitivity to small or sparse prostatic cancer (PCa). Thus, our aim was to determine the influence of voxel size to cDWI with high b value, and directly compare image quality and capability for PCa detection with aDWI with high b-value as obtained conventional and reduced voxel sizes at 3T MR system.

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