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Abstract #1541

Multi-b-value diffusion weighted imaging acquired on a 3T MR scanner: comparison of the apparent diffusion coefficient in prostate cancer detection and the contribution of b-value images in ADC map interpretation.

Thomas de Perrot 1 , Bndicte M A Delattre 1 , Lindsey A Crowe 1 , Iris Friedli 1 , Marc Pusztaszeri 2 , Jean-Christophe Tille 2 , Christophe Iselin 3 , and Jean-Paul Valle 1

1 Division of Radiology, Geneva University Hospital, Geneva, Switzerland, 2 Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland, 3 Division of Urologic Surgery, Geneva University Hospital, Geneva, Switzerland

We examined the influence of b-value on ADC map performance for prostate cancer in a retrospective study. We have demonstrated that the flow-sensitive ADC map was superior to the flow-insensitive ADC map for prostate cancer detection and that multi-b ADC maps in comparison with a 2-b ADC map did not improve detection. In addition, b-value images provide complementary information and improve over the ADC map alone in cancer detection. This study provides a statistical demonstration of the commonly accepted practice to look for enhanced signal in cancer on the high b-values images in the area of reduced ADC.

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