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Abstract #1569

THE RELIABILITY OF MAGNETIC RESONANCE ELASTOGRAPHY (MRE) USING MULTISLICE 2D SPIN-ECHO ECHO-PLANAR IMAGING (SE-EPI) AND 3D INVERSION RECONSTRUCTION FOR ASSESSING RENAL STIFFNESS

Gavin Low 1,2 , Nicola Eve Owen 3 , Ilse Joubert 1 , Andrew J Patterson 1 , Kevin J Glaser 4 , Martin J Graves 1 , Graeme J.M. Alexander 3 , and David J Lomas 1

1 Radiology, Addenbrooke's Hospital, Cambridge, England, United Kingdom, 2 University of Alberta, Edmonton, Alberta, Canada, 3 Hepatology & Gastroenterology, Addenbrooke's Hospital, Cambridge, England, United Kingdom, 4 Radiology, Mayo Clinic, Minnesota, United States

The purpose of this study was to evaluate the reliability of a novel renal MRE (magnetic resonance elastography) technique using spin-echo echo-planar imaging (SE-EPI) in healthy volunteers. The study population included 16 adult volunteers. Each participant underwent two renal MRE examinations, within a 30 minute interval between examinations. Two radiologists acted as independent readers. The test-retest repeatability and the inter-rater agreement of the renal MRE technique were assessed using Bland Altman, the within subject coefficient of variation, the coefficient of repeatability, and interclass correlation coefficient analysis. Our findings showed that SE-EPI renal MRE is a reliable imaging technique.

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