Abstract #1582
Robust and Noninvasive Measurement of Renal Perfusion using Multi-Phase Pseudo-Continuous Arterial Spin Labeling
William Jeffrey Triffo 1 and Youngkyoo Jung 2
1
Department of Radiology, Wake Forest School
of Medicine, Winston Salem, NC, United States,
2
Departments
of Radiology and Biomedical Engineering, Wake Forest
School of Medicine, Winston Salem, NC, United States
The accuracy of pseudo-continuous ASL (PCASL) methods is
sensitive to phase errors related to off-resonance
effects at the tagging plane. Respiratory motion is also
a well-known problem in body imaging. We present the
application of multi-phase PCASL (MP-PCASL) to study
renal perfusion, along with a masked object registration
algorithm for semi-automatic alignment after breath-hold
acquisition. Example data illustrating off-resonance
induced errors in the PCASL estimation of renal blood
flow and the associated phase errors are provided.
MP-PCASL provides a robust alternative that is
insensitive to such errors.
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