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Abstract #1608

Spatially-Constrained Incoherent Motion (SCIM) Model Improves the Robustness of Fast and Slow Diffusion Parameter Estimation from DW-MRI Data in Various Multiple b-Value Acquisition Protocols

Vahid Taimouri 1 , Moti Freiman 1 , and Simon K Warfield 1

1 Radiology, Boston Children's Hospital, Boston, MA, United States

The Spatially-Constrained Incoherent Motion (SCIM) model aims to improve the quality of the fast and slow diffusion parameter estimates by utilizing a spatial homogeneity of the signal decay parameters as an informative prior to guide the estimation, and effectively estimates parametric maps representing the signal decay model using the Fusion Bootstrap Moves (FBM) solver. Here, we aim at evaluation of the SCIM model on improving the robustness of fast and slow diffusion parameter estimates in the ileum against acquisition protocols that utilize different choices of b-values.

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