Abstract #1624
Quantification of Brown Adipose Tissue in DIXON Water-Fat Separation and T2* Mapping
Defeng Wang 1 , Ka Long Ko 1 , Steve CN Hui 1 , Lin Shi 2,3 , and Winnie CW Chu 1
1
Dept of Imaging and Interventional
Radiology, The Chinese University of Hong Kong, Shatin,
NT, Hong Kong,
2
Dept
of Medicine and Therapeutics, The Chinese University of
Hong Kong, Shatin, NT, Hong Kong,
3
Chow
Yuk Ho Technology Centre for Innovative Medicine, The
Chinese University of Hong Kong, Shatin, NT, Hong Kong
The purpose of this study was to verify the accuracy of
using water-fat separation method and T2* mapping to
quantify brown adipose tissue. A water-fat separation
MRI sequence and T2* MR imaging technique was applied on
obese teenagers and control. Fat-fraction signal and T2*
mapping were generated with multiecho scanning and
specially focused on interscapular-supraclavicular
region. Results indicated volume of BAT was
significantly less in obese subjects than that in normal
controls. The proposed algorithm could accurately
measure the volume of BAT in human and could be served
as an alternative to detect BAT and WAT.
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