Abstract #1623
Visualizing and quantifying human fat digestion with IDEAL
Dian Liu 1 , Helen Louise Parker 2 , Jelena Curcic 1,2 , Sebastian Kozerke 1 , and Andreas Steingoetter 1,2
1
Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland,
2
Division
of Gastroenterology and Hepatology, University Hospital
Zurich, Zurich, Switzerland
This study uses chemical shift-encoded imaging by IDEAL
to visualize and quantify the influence of intragastric
stability of fat emulsions on the dynamics and structure
of gastric luminal content and the related fat emptying
into the duodenum. The different intragastric stability
of the emulsions resulted in different structuring of
intraluminal content and different emptying patterns,
which resulted in bi-phasic and significantly faster
emptying of gastric content and highly variable gastric
and duodenal fat fractions for the acid unstable
emulsion. No temporal effect was detected for duodenal
content volume or fat fraction between the emulsions.
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