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Abstract #1626

Improved retinal shape detection using high-resolution MRI compared to partial coherence interferometry

Jan-Willem M Beenakker 1,2 , Mihai State 3 , Denis P Shamonin 4 , Marrie van der Mooren 3 , Berend C Stoel 4 , Andrew G Webb 1 , Gregorius PM Luyten 2 , and Patricia Piers 3

1 Department of Radiology, C.J.Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 2 Department of Ophthalmology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 3 AMO Groningen BV, Groningen, Netherlands, 4 Department of Radiology, devision of Image Processing, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

Current techniques in ophthalmology, such as PCI (partial coherence interferometry), cannot accurately measure the retinal shape because refraction causes systematic errors for off-axis measurements. We assessed these errors by measuring the left eye of 16 volunteers using high-resolution ocular MRI, which is not influenced by refraction, and PCI. The on-axis data shows the high accuracy of ocular MRI (systematic error 0.08mm), while off-axis measurements show large systematic differences between the techniques. This shows the importance of MRI as the gold-standard for three-dimensional retinal shape characterisation.

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