MR Compatible Electrode for RF Hyperthermia with Capacitive Coupling: Feasibility Demonstration

The radio-frequency hyperthermia treatment with capacitive driving is now emerging as a noninvasive cancer treatment method. The tumorous tissue having higher ionic concentration have higher electric conductivity than the normal tissue. When the RF electric field is applied, the more electric current is drawn by the tumor cell resulting in the increased temperature around the tumor. This process could be carried out more safely with accuracy if we can monitor the treatment process including the temperature. We have studied the technical feasibility of developing MR compatible electrodes which can be used for RF hyperthermia in the MR systems with proper switching mechanism without affecting MR signal reception. A prototype animal 13.56 MHz capacitive RF hyperthermia system was operated with MR image acquisition capability using a 3.0-T MRI system (Achieva 3.0 T, Philips). We have designed, constructed, and tested experimentally a new RF electrode with switching resonant circuits working at 13.56 MHz without affecting the MR image acquisition at 128 MHz.

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