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Abstract #1654

High speed, high sensitivity MR thermometry using a balanced steady-state free precession pulse sequence

Yuan Zheng 1 and G. Wilson Miller 2

1 Physics, University of Virginia, Charlottesville, VA, United States, 2 Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

We have developed a proton resonance frequency shift (PRFS) based MR thermometry technique that collects temperature-sensitive phase images using a balanced steady-state free precession (bSSFP) pulse sequence. Our technique makes use of the sharp phase transition of bSSFP images over a narrow frequency range near resonance. Although the phase transition is non-linear, the phase change can be accurately mapped to PRFS (and thus temperature) using a pre-scanned phase transition curve. We performed phantom experiments using MR-guided focused ultrasound, to demonstrate the advantages of our bSSFP technique over conventional GRE-based methods for measuring small, fast temperature changes at the ultrasound focus.

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