Abstract #1682
B 1 + Field Mapping Improves Accuracy of T 1 Measurements in Phantoms and Normal Breast at 3.0 T
Jennifer G. Whisenant 1 , Lori R. Arlinghaus 1 , Richard D. Dortch 1 , William A. Grissom 1 , Gregory S. Karczmar 2 , and Thomas E. Yankeelov 1
1
Vanderbilt University, Nashville, TN, United
States,
2
University
of Chicago, Chicago, IL, United States
This study evaluated the effect of
B
1
+
correction
on
T
1
measurements
calculated from variable flip angle (VFA) data in
phantoms and
in
vivo
. Additionally, the accuracy of these
measurements was compared to
T
1
values
from inversion recovery (IR) data. On average, 31% error
was observed between IR and uncorrected VFA data in both
phantoms and in vivo, which was significantly reduced to
6% (P<0.001) when applying a
B
1
+
correction.
IR measurements of
T
1
are
very robust, yet the long acquisition times limit
clinical utility. Therefore, these data suggest that the
VFA method with
B
1
+
correction
is a suitable alternative.
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