Abstract #1684
Proton density mapping: Removing receive-inhomogeneity using multi-coil information and T1 regularization
Aviv Mezer 1 , Ariel Rokem 2 , Trevor Hastie 2 , and Brian Wandell 2
1
Edmond and Lily Safra Center for Brain
Sciences, The Hebrew University, Jerusalem, Israel,
2
Stanford
university, CA, United States
Proton density is the most basic MRI measure,
representing the amount of water protons in each voxel.
Water content differs between tissue types, and changes
during development and in disease. Using simulation we
find that in the presence of noise, combining parallel
imaging, smoothness assumptions, and the biophysical
regularization together generates the most accurate
estimates of both coil sensitivity maps and PD. We
confirm the high accuracy when using multiple coils and
T1-regularization on data from a phantom and a living
human brain.
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