Abstract #1697
The optimal curve-fitting models for liver T2 measurements iron overload in β-thalassemia major patients
Busakol Ngammuang 1 , Kittichai Wantanajittikul 2 , Monruedee Tapanya 1 , Suchaya Silvilairat 3 , Pimlak Charoenkwan 3 , and Suwit Saekho 1
1
Department of Radiological Technology,
Faculty of Associated Medical Sciences, Chiang Mai
University, Chiang Mai, Thailand,
2
Biomedical
Engineering Center, Faculty of Engineering, Chiang Mai
University, Chiang Mai, Thailand,
3
Department
of Pediatrics, Faculty of Medicine, Chiang Mai
University, Chiang Mai, Thailand
T2' is another MRI parameter that reflects solely to the
magnetic inhomogeneity and shows high correlations to
LIC, T2 and T2*. We compare liver T2' obtained from ROI
and pixel based method by three curve-fitting models,
mono-exponential, offset and truncation model. Fifteen β
thalassemia major patients were study. Results showed
that ROI based method with offset curve fitting model
potentially provided no significantly difference
outcomes to those of pixel based method for liver T2
measurements.
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