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Abstract #1696

Uncertainty Quantification of Multi-Site T1 Measurements with Polyvinylpyrrolidone (PVP) Phantom and Human Brain Using Wild Bootstrap Analysis

Congyu Liao 1 , Meng Chen 1 , Darong Zhu 2 , Hongjian He 1 , Song Chen 1 , Qiuping Ding 1 , and Jianhui Zhong 1

1 Center for Brain Imaging Science and Technology, Zhejiang University, Hangzhou, Zhejiang, China, 2 Hangzhou First People's Hospital, Zhejiang, China

In this study, T1 mapping of a phantom with different concentration of Polyvinylpyrrolidone (PVP) solutions and a volunteer were acquired in two different 3T scanners using DESPOT1 method, and wild bootstrap analysis was used to assess both intra- and inter-site uncertainty of quantitative T1 measurements.

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