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Abstract #1707

Measurement of Brain Iron and Calcium using MR QSM and CT: validation using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES)

Jingwei Zhang 1,2 , Cynthia Wisnieff 1,2 , Becky Schur 3 , Lu Zhengrong 3 , David Pitt 4 , and Yi Wang 1,2

1 Biomedical Engineering, Cornell University, New York, New York, United States, 2 Radiology, Weill Cornell Medical College, New York, New York, United States, 3 Biomolecular Engineering, Case Western Reserve University, Ohio, United States, 4 Neurology, Yale School of Medicine, CT, United States

This study aims at demonstrating the feasibility of correcting calcium susceptibility for more accurate [Fe] maps utilizing both QSM and CT images in brain specimens. The results are compared with ICP-OES results served as the golden standard.

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