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Abstract #1708

2D-segmented, multi-TE 3D-EPI for high-resolution R 2 * and quantitative susceptibility mapping at 7 Tesla

Rdiger Stirnberg 1 , Julio Acosta-Cabronero 2 , Benedikt A. Poser 3 , and Tony Stcker 1,4

1 German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2 German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany, 3 Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 4 Department of Physics and Astronomy, University of Bonn, Bonn, Germany

Recently, the feasibility of quantitative susceptibility mapping (QSM) at 3 Tesla using segmented 3D-EPI requiring only a fraction of conventional gradient echo (GRE) acquisition times, has been demonstrated. Moving to higher field strengths usually involves higher spatial resolutions and shorter echo times. The use of additional in-plane segmentation in 3D-EPI is proposed here to meet both requirements at 7 Tesla. Multiple R 2 * weightings further increase the sequence flexibility. QSM results at 0.8mm in-plane resolution show that more than one EPI average is hardly needed when compared to GRE. More advanced applications, such as susceptibility tensor imaging, thus become feasible.

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