Limitations of Accelerated QSM by FOV Restriction to Deep Gray Matter
Ahmed M. Elkady 1 , Hongfu Sun 1 , and Alan H. Wilman 1
Dept. of Biomedical Engineering, University
of Alberta, Edmonton, AB, Canada
Field of View (FOV) restriction to deep Gray Matter (GM)
only would significantly accelerate Quantitative
Susceptibility Mapping (QSM) acquisitions, facilitating
its clinical use in diseases such as Multiple Sclerosis.
However, nonlocal effects of dipole fields require
careful examination of accelerated QSM through FOV
restriction, which were studied through simulations and
in vivo MRI acquisitions in each direction (x,y,z). FOV
restriction parallel to the main field (z-axis) was
found to significantly reduce QSM accuracy. Optimally,
coronal FOV restriction (y-axis) should be used for
accelerated QSM, requiring a FOV of 133mm or more to
obtain accurate QSM results of deep GM.
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