Abstract #1724
Susceptibility quantification for ferritin and Fe 3 O 4 nanoparticles: Observation of hyperfine shift in phase images and comparison between phase measurement and CISSCO
He Xie 1 , Yu-Chung Norman Cheng 2 , Ching-Yi Hsieh 2 , Paul Kokeny 3 , and E.Mark Haacke 2
1
Physics and Astronomy, Wayne State
University, Detroit, Michigan, United States,
2
Radiology,
Wayne State University, Detroit, Michigan, United
States,
3
Biomedical
Engineering, Wayne State University, Detroit, Michigan,
United States
This study focused on phase measurement in
susceptibility quantification. Phase shift due to
hyperfine structure was observed in ferritin and iron
oxide nanoparticles. Susceptibility quantification
results from phase measurement were compared with
results from our CISSCO method. The results indicates
that a more careful work might be needed before QSM
methods can be applied to the phase images. This study
also suggests that CISSCO is a reliable quantification
method for magnetic susceptibility.
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