Meeting Banner
Abstract #1723

A Dixon Method for Positive Contrast Imaging of Very Small Superparamagnetic Iron Oxide Nanoparticles in MRI

Dirk Krger 1 , Silvia Lorrio Gonzlez 1 , and Ren M. Botnar 1

1 Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom

The aim of this project is to develop and validate a Dixon MR imaging technique to achieve positive contrast of very small superparamagnetic iron oxide nanoparticles (VSOPs). We assessed the proposed method in a phantom study and compared the results with three established positive contrast imaging techniques. The reference techniques were GRadient-echo Acquisition for Superparamagnetic particles (GRASP), Inversion Recovery with ON-resonant water suppression (IRON), and Susceptibility Gradient Mapping (SGM). The Dixon method demonstrated superior sensitivity, relative ease of implementation and reliability.

This abstract and the presentation materials are available to members only; a login is required.

Join Here