Modulation of Inter-Slice Frequency Offsets for Magnetization Transfer Ratio Imaging

Recently, an inter-slice MT imaging using bSSFP has been proposed as a new method for MT imaging. To advance the inter-slice MT imaging to quantitative MT, we tested feasibility of modulation of inter-slice frequency offsets by changing RF duration and inter-slice gap. Experimental results showed that MT images from different offset frequencies could be acquired by changing the RF duration and inter-slice gap, which was demonstrated in phantom and in vivo brain. The proposed technique can enable us to acquire MT images at multiple offset frequencies within a reasonable scan time and thus may be useful for quantitative MT.

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