Abstract #1744
Initial experience using Magnetization Transfer with Iterative Decomposition of water and fat with Echo Asymmetry and Least-squares estimation (MT-IDEAL) in the abdomen.
David ML Lilburn 1 , Annette S Cooper 1 , Philip Murphy 2 , Christopher DJ Sinclair 3 , Scott I Semple 1,4 , and Robert L Janiczek 2
1
Clinical Research Imaging Centre, University
of Edinburgh, Edinburgh, East Lothian, United Kingdom,
2
Experimental
Medicine Imaging, GlaxoSmithKline, Uxbridge, Middlesex,
United Kingdom,
3
Institute
of Neurology, University College London, London, United
Kingdom,
4
BHF
Centre for Cardiovascular Science, University of
Edinburgh, Edinburgh, East Lothian, United Kingdom
Clinical magnetization transfer (MT) imaging within the
abdomen has proven to lack sensitivity to detect liver
fibrosis, possibly due to the confounding effect of
lipid infiltration. Here a new method, which aims to
remove the MT dependence on lipid concentration through
integration of IDEAL fat/water separation, is employed.
This study assesses the feasibility of MT-IDEAL imaging
in the abdomen and compares resultant MTR values using
standard MT methods and the MT-IDEAL paradigm. It is
hoped that this will eventually allow for investigation
of pathological changes in fat content and fibrosis
within intra-abdominal organs in a wide range of
diseases.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
