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Abstract #1921

Disentangling different Gadolinium concentrations: a comparison between High Field and Very Low Field MRI.

Allegra Conti 1 , Massimo Caulo 1,2 , Angelo Galante 3 , Vittorio Pizzella 1,2 , Gian Luca Romani 1,2 , and Stefania Della Penna 1,2

1 Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio Univ. of Chieti and Pescara, Chieti, CH, Italy, 2 Institute for Advanced Biomedical Technologies (ITAB), G. D'Annunzio Univ. of Chieti and Pescara, Chieti, CH, Italy, 3 MESVA, Department of Life, Health & Environmental Sciences, L'Aquila University, L'Aquila, AQ, Italy

Gadolinium based Contrast Agents are routinely used in MRI to improve the diagnostic accuracy of brain pathologies. Recently, Very and Ultra Low Field-MRI scanners have been developed, and the advantages of these system in the study of tissue contrast have been suggested. Here we show how the contrast of T1-weighted images of different concentrations of MultiHance and Gadovist changes varying the applied field (8.9 mT, 0.2 T, 1. 5 T ,3 T). Results demonstrate that signal contrast does not improve at high field strengths, and that longitudinal relaxation rate-maps at ULF are the best instruments to distinguish different Gd-concentrations.

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