Abstract #1947
Long echo time in-vivo spectroscopy without J-modulation
Clark Lemke 1 , Aaron Hess 2 , Jamie Near 3 , Stuart Clare 1 , Peter Jezzard 1 , and Uzay Emir 1
1
FMRIB, University of Oxford, Oxford,
Oxfordshire, United Kingdom,
2
OCMR,
University of Oxford, Oxford, Oxfordshire, United
Kingdom,
3
Douglas
Institute, McGill University, Verdun, Quebec, Canada
An
in-vivo
implementation
of a novel technique to acquire long echo time
spectroscopy without J-modulation has been compared with
conventional PRESS at short (30 ms) and long (60 ms)
echo times. The novel technique, entitled PRESS-JR,
repeats a so-called perfect-echo refocusing unit in
order to remove J-modulation at arbitrary echo time. At
long echo time, PRESS-JR produces desirable spectra
without baseline contamination or J-modulation. This
technique could be very useful for disease conditions
such as tumors or epilepsy since larger and more complex
baseline signals result in decreased quantification
accuracy for coupled metabolites at short echo times.
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