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Abstract #1947

Long echo time in-vivo spectroscopy without J-modulation

Clark Lemke 1 , Aaron Hess 2 , Jamie Near 3 , Stuart Clare 1 , Peter Jezzard 1 , and Uzay Emir 1

1 FMRIB, University of Oxford, Oxford, Oxfordshire, United Kingdom, 2 OCMR, University of Oxford, Oxford, Oxfordshire, United Kingdom, 3 Douglas Institute, McGill University, Verdun, Quebec, Canada

An in-vivo implementation of a novel technique to acquire long echo time spectroscopy without J-modulation has been compared with conventional PRESS at short (30 ms) and long (60 ms) echo times. The novel technique, entitled PRESS-JR, repeats a so-called perfect-echo refocusing unit in order to remove J-modulation at arbitrary echo time. At long echo time, PRESS-JR produces desirable spectra without baseline contamination or J-modulation. This technique could be very useful for disease conditions such as tumors or epilepsy since larger and more complex baseline signals result in decreased quantification accuracy for coupled metabolites at short echo times.

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