Quantitation error in 1 H MRS caused by B 1 inhomogeneity and chemical shift displacement at high B 0 field

High signal to noise ratio and good peak resolution are significant features in ¹ H MRS at high B ₀ field. However, large chemical displacement and B ₁ inhomogeneity may weight a peak on a localized spectrum by different reception sensitivity due to chemical shift. For example, magnitudes of peaks of NAA and Cr are weighed by the different values and this may lead to quantitation error. In this work, we will demonstrate this error in phantom experiments at 4.7 T. We will also demonstrate correction method using the profile of reception sensitivity measured by water signals.

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