Mapping the Visual Pathway in the Mouse Brain using Snapshot fMRI

Mouse brain fMRI has made significant progress over the last 10 years, but remains technically challenging and requires further efforts to improve data acquisition. In this work we demonstrate the use of visual stimulation as a viable task for fMRI of the mouse brain, with robust responses in the mid-brain (superior colliculus, lateral geniculate nuclei), mapping the visual pathway. We also examine the use of GE-EPI with multiple snapshots (compressed segments) as a way of reducing image distortion due to B ₀ inhomogeneities at the point of acquisition.

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