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Abstract #2074

Factors influencing learning to self-regulate brain activity using real-time fMRI: comparison between conscious strategy and contingent feedback

Pradyumna Seplveda 1,2 , Ranganatha Sitaram 3,4 , Mohit Rana 3,5 , Toms Ossandn 6 , Marcelo Anda 1,7 , Cristin Montalba 1 , Sergio Uribe 1,7 , Pablo Irarrzaval 1,2 , Sergio Ruiz 4,6 , and Cristin Tejos 1,2

1 Biomedical Imaging Center, Pontificia Universidad Catlica de Chile, Santiago, Chile, 2 Department of Electrical Engineering, Pontificia Universidad Catlica de Chile, Santiago, Chile, 3 Department of Biomedical Engineering, University of Florida, Gainesville, Florida, United States, 4 Institute of Medical Psychology and Behavioral Neurobiology, University of Tbingen, Tbingen, Germany, 5 Graduate School of Neural & Behavioural Sciences, International Max Planck Research School, University of Tbingen, Tbingen, Germany, 6 Department of Psychiatry, Faculty of Medicine, Interdisciplinary Center for Neuroscience, Pontificia Universidad Catlica de Chile, Santiago, Chile, 7 Radiology Department, Faculty of Medicine, Pontificia Universidad Catlica de Chile, Santiago, Chile

Healthy subjects and patients can self-regulate brain activity locally or globally using real time fMRI neurofeedback (rtfMRI NF), often accompanied by observable behavioral changes. Furthermore, new therapeutic and research applications have encouraged a growing number of studies using rtfMRI NF. Despite the interest, the relevance of different factors in the self-regulation learning process is yet to be known. In this study we compared the influence of using a conscious mental strategy during neurofeedback versus pure contingent feedback. Results indicate that the use of a conscious strategy does not necessarily improve learning with respect to only NF.

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