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Abstract #2075

Functional connectivity in Task Switching Paradigm

Mitsunobu Kunimi 1 , Sachiko Kiyama 1 , and Toshiharu Nakai 1

1 National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

This study attempted to demonstrate the extent of the task load-dependent augmentation of brain activation and the change of functional connectivity during the TSP. Twenty healthy young adults (mean age: 22.80 }3.44, 9 males) participated in the study. The significant activation was observed in the frontal and parietal region and it was augmented as task load increased. In addition, the functional connectivity was extended depending on task load. These results were considered that the network of these regions works as a central executive, and it controls switch of attention, task-set reconfiguration and inhibition during TSP.

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