Meeting Banner
Abstract #2086

Functional Connectivity Analysis: Performance Comparison of Gradient and Spin Echo EPI Simultaneously Acquired

Brice Fernandez 1 , Victor Spoormaker 2 , Philipp Smann 2 , and Michael Czisch 2

1 Applications & Workflow, GE Healthcare, Munich, Germany, 2 Neuroimaging Unit, Max Planck Institute of Psychiatry, Munich, Germany

Resting state functional connectivity is an attractive tool to study affective and mood disorders. Gradient-echo EPI (GRE-EPI) is affected by strong signal drops in brain regions critical for emotional processing. Spin-echo EPI (SE-EPI) is known to not suffer from this problem. Here, we use a Hybrid EPI pulse sequence to simultaneously acquire both the GRE-EPI and the SE-EPI. The comparison of both acquisition methods shows that meaningful signal fluctuations can be recovered in susceptibility affected brain regions using SE-EPI, while minor differences in functional connectivity were observed for unaffected brain areas. Furthermore, GRE-EPI is more prone to global signal artefacts.

This abstract and the presentation materials are available to members only; a login is required.

Join Here