Abstract #2128
Physiological Modulators of Resting-State MRI Functional Connectivity
Powell Pui Wai Chu 1,2 , Ali M. Golestani 1 , Jonathan B. Kwinta 1,2 , Yasha B. Khatamian 1 , and Jean J. Chen 1,2
1
Rotman Research Institute, Baycrest,
Toronto, Ontario, Canada,
2
Medical
Biophysics, University of Toronto, Toronto, Ontario,
Canada
Resting-state fMRI functional connectivity (rs-fcMRI)
measurements are based on the BOLD fMRI signal, which is
influenced by systemic physiological variability. Thus,
fcMRI data interpretation may be difficult across
different subjects without the knowledge of these
physiological influences. In this work, in order to
improve the reliability of rs-fcMRI measurements, we
assess the influence of physiological factors including
baseline cerebral blood flow and venous blood
oxygenation on functional connectivity estimates. We
found a significance relationship between rs-fcMRI
values and the above two physiological variables.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
